Internalized compartments encapsulated nanogels for targeted drug delivery
نویسندگان
چکیده
منابع مشابه
Galactose-functionalized multi-responsive nanogels for hepatoma-targeted drug delivery.
We report here a hepatoma-targeting multi-responsive biodegradable crosslinked nanogel, poly(6-O-vinyladipoyl-D-galactose-ss-N-vinylcaprolactam-ss-methacrylic acid) P(ODGal-VCL-MAA), using a combination of enzymatic transesterification and emulsion copolymerization for intracellular drug delivery. The nanogel exhibited redox, pH and temperature-responsive properties, which can be adjusted by va...
متن کاملTargeted nanogels: a versatile platform for drug delivery to tumors.
Although nanoparticle-based drug delivery formulations can improve the effectiveness and safety of certain anticancer drugs, many drugs, due to their chemical composition, are unsuitable for nanoparticle loading. Here, we describe a targeted nanogel drug delivery platform that can (i) encapsulate a wide range of drug chemotypes, including biological, small molecule, and cytotoxic agents; (ii) d...
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ژورنال
عنوان ژورنال: Nanoscale
سال: 2016
ISSN: 2040-3364,2040-3372
DOI: 10.1039/c5nr08895j